Researcher's Profile


     ORCID Follow

Research Outline      2017-04-25 16:49:08

As a plastic surgeon, Dr. Cheng often deals with various clinical problems with human tissue deficiency. Since current reconstructive procedures have their limitations, Dr. Cheng’s research has been focused on applying adipose-derived stem cells (ASCs) in regenerative medicine. Stem cells have been shown to be capable of growing efficiently and differentiating into various kinds of cell. Since ASCs can be harvested abundantly with minimally invasive procedures, these cells represent a good candidate for application in tissue regeneration.

Dr. Cheng joined Professor Farshid Guilak’s bioengineering laboratory in Duke University Medical Center as a postdoctoral fellow in 2007, and he successfully applied ASCs on native tissue-derived scaffolds to make cartilage-like tissue. This series of study have been published in Tissue Engineering and Regenerative Medicine. After returning to Taiwan in 2009, Dr. Cheng further investigated the scaffold-free 3D culture techniques to fabricate ASC spheroids and sheets. His team has successfully applied ASC spheroids and sheets to enhance tissue regeneration in animal models of cutaneous wound healing. This series of study have been published in Biomaterials and Stem Cells Translational Medicine. Currently, he aims at the clinical application of stem cell-based techniques to promote tissue regeneration, especially wound healing.